Reference | FQPLYEVH (43)

Our primary objectives were to (i) acquire a comprehensive understanding of poultry and litter microbiomes and resistomes as a function of the growth stage, (ii) assess the efect of therapeutic and prophylactic antibiotics on poultry microbiomes and resistomes, and (iii) determine the potential synergistic efects of combined use. Longitudinal sampling of individual birds was applied to provide evidence of causal efects. We hypothesized that higher rates of AMR would accumulate throughout the production cycle in groups treated with AGPs, compared to short-term antibiotic treatment or the non-treated control groups.

The study was conducted between May and June 2018 in an experimental poultry house, simulating a full commercial broiler production cycle. The poultry house was divided into 12 pens with poultry mesh, with six pens on each side separated by a 2-m–wide service lane.

AST Method: Broth Microdilution

Reference explicitly reports AST breakpoints: None

Reference reports using a MIC table: None