Ladely, Scott R.; Harrison, Mark A.; Fedorka-Cray, Paula J.; Berrang, Mark E.; Englen, Mark D.; Meinersmann, Richard J. (United States of America)
Journal of Food Protection (2007)
In three replicated studies, day-of-hatch chicks were exposed to macrolide-susceptible C. jejuni or C. coli. At 2 weeks of age, tylosin was administered at subtherapeutic (22 ppm, continuously in the diet) or therapeutic concentrations (529 ppm, in the drinking water for 5 days). Broilers were sacrificed weekly.
At 2 weeks of age, prior to medication treatments, and at 3, 4, 5, and 6 weeks of age, five broilers per group were necropsied. Ceca were removed aseptically, placed in Whirl-Pak bags (Nasco, Modesto, Calif.) on ice, and processed within 2 h. Total and resistant Campylobacter spp. were enumerated from individual ceca plus contents as described below.
AST Method: None
Reference explicitly reports AST breakpoints: True
Reference reports using a MIC table: True
Is Excluded: False
| Country | Sub-Region | Sub-Region Detail |
|---|---|---|
| United States of America | Georgia (State) | None |
| ID | Note | Resolution |
|---|
| Title | Host | Host | Production Stage | Description | ROs |
|---|---|---|---|---|---|
| Tylosin Use | Chicken | Broilers | Farm | Distribution of erythromycin resistance for C. jejuni and C. coli recovered from ceca receiving either subtherapeutic (22 ppm of tylosin phosphate) or therapeutic (529 ppm of tylosin tartrate) concentrations of tylosin. Using week 6 age. | 1 |