Reference | Nair_2018_CanaVeteJour (10315)

A clinical trial investigating the impact of in-feed flavophospholipol on Salmonella shedding and antimicrobial resistance in pigs.


Nair, Saranya and Farzan, Abdolvahab and O'Sullivan, Terri L. and Friendship, Robert M. (Canada)

Canadian Veterinary Journal (2018)

Reference


Forty-five pigs at 10 wk of age were obtained from a commercial farm in which Salmonella shedding in pigs was known to be prevalent based on previous diagnostic work. Randomly assigned to 1 of 9 pens (5 pigs/pen). The treatment group consisted of 5 pens (n = 25 pigs) and these pigs were provided with a diet containing 4 ppm of flavophospholipol (Flavomycin; Huvepharma, distributed by Bio Agri Mix, Mitchell, Ontario). The control group (n = 20 pigs) housed in 4 pens received an identical diet but without the medication.

Over the 10-week period (weeks 1 to 11), fecal samples or rectal swabs were collected weekly from the 45 pigs.

AST Method: Broth Microdilution

Reference explicitly reports AST breakpoints: True

Reference reports using a MIC table: False

Is Excluded: False

Country Sub-Region Sub-Region Detail
Canada Ontario (Province) None
ID Note Resolution

Factors


Title Host Host Production Stage Description ROs
Flavophospholipol use Swine Grower-finisher Farm 4 ppm in feed (grow-finish pigs) for 10 weeks. 11
Flavophospholipol use Swine Grower-finisher Farm 4 ppm in feed (grow-finish pigs) for 10 weeks. Week 4 is latest data presented for Salmonella. 4
Flavophospholipol use Swine Grower-finisher Farm 4 ppm in feed (grow-finish pigs) for 10 weeks. Week 4 is latest data presented for Salmonella. Pigs obtained from farm w/history of salmonellosis. Referent group AMR+ = 0.98. 1
Flavophospholipol use Swine Grower-finisher Farm 4 ppm in feed (grow-finish pigs) for 3 weeks. 4