Reference | Dealy_1977_Joofansc_1 (10276)

Twenty male Holstein calves, 5 to 6 weeks of age were purchased at auction. The nonmedicated cattle developer was a commercial feed containing 14% protein, 2.5% fat, and 9.0% fiber. The medicated test feed was the same cattle developer supplemented with 44.0 mg bambermycins per kilogram. Salmonella typhimurium was used as the infecting organism. Each animal received 3.0 x 1012 organisms. The calves were randomly allotted by weight into four treatment groups. Seven calves were assigned to the Salmonella infected Treatment Groups A (nonmedicated feed) and B (bambermycins medicated feed). Three calves were assigned to the two identically treated uninfected environmental control groups included in order to monitor for cross-contamination. Management practices were the same for all groups.

Rectal fecal samples were collected with sterile surgical gloves from each calf on two separate occasions before the start of the trial. All calves were negative for Salmonella. Fecal samples were taken from all calves on days 2, 4, 7, 10, 14, 21, 28, 35, 42, 49 and 56 postinfection.

AST Method: Unclear

Reference explicitly reports AST breakpoints: False

Reference reports using a MIC table: False