Reference | Dealy_1977_Joofansc (10275)

The animals used were 14 male Holstein calves, 5 to 6 weeks of age, purchased at auction. Previous antibiotic treatment was unknown. The calves were housed in separate stalls inside a ventilated barn. The nonmedicated cattle developer was a commercial feed containing grain products, plant proteins, cane molasses and minerals. The medicated test feed was the same cattle developer supplemented with 44.0 mg bambermycins per kilogram. The calves were fed 450 g of commercial feed twice daily. The infecting strain of Salmonella typhimurium strain was used to infect all the calves, and carried plasmid resistance to ampicillin, streptomycin, oxytetracycline and triple sulfa. This organism was sensitive to chloramphenicol, nitrofurantoin, gentamycin, neomycin, colistin and bambermycins.

Fecal samples for enumeration of E. coli and antibacterial susceptibility were collected in sterile surgical gloves from all calves on two separate occasions before the experimental period and weekly thereafter until the conclusion of the trial at 56 days postinfection.

AST Method: Unclear

Reference explicitly reports AST breakpoints: False

Reference reports using a MIC table: False