Cameron-Veas, Karla and Sol-Gins, Marc and Moreno, Miguel A. and Fraile, Lorenzo and Migura-Garcia, Lourdes (Spain)
Applied and Environmental Microbiology (2015)
This study was conducted on a conventional commercialpig farm in the northeast of Spain.Sixty-eightsows were housed in a climate-controlled house. After farrowing, a total of100 7-day-old piglets from 10 different sows were spatially divided intotwo groups: untreated controls (n50) and animals parenterally treated(n50) with ceftiofur (5 mg/kg of body weight in one shot). Duringthe fattening period (day 70), each of the original two groupswas subdivided into two (Table 2). A treatment with amoxicillin (May-moxi;Laboratorios Maymó) was administered in feed for 14 days to twoof the four resulting groups (10 mg/kg of body weight/day), consisting ofthe following: group 1, untreated control group, or animals that did notreceive any treatment with beta-lactams (n20); group 2, animals orallytreated with amoxicillin during finishing (n26); group 3, animals par-enterally treated with ceftiofur during preweaning (n20); and group 4,animals treated with ceftiofur and amoxicillin (n26).
Fecal samples were taken manually fromthe rectum of piglets on six occasions: before treatment (day 0) and at days2, 7, 14, 21, and 42 posttreatment of ceftiofur. Fecalsamples were taken from all animals before administration of amoxicillin(day 0) and on days 2, 7, 14, 21, 45, and 73 posttreatment. A final samplingwas performed at the time of slaughter.
AST Method: None
Reference explicitly reports AST breakpoints: False
Reference reports using a MIC table: False
Is Excluded: False
Country | Sub-Region | Sub-Region Detail |
---|---|---|
Spain | Other (Other) | North-east of Spain |
ID | Note | Resolution |
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Title | Host | Host | Production Stage | Description | ROs |
---|---|---|---|---|---|
Ceftiofur use | Swine | Piglets | Farm | 5 mg/kg of body weight parenterally during preweaning. Sampling day 14 (pigs age 20-22 days) | 1 |
Amoxicillin use | Swine | Weaners | Farm | 10 mg/kg of body weight/day in feed for 14 days (pigs age 77 days) | 1 |
Ceftiofur use | Swine | Weaners | Farm | 5 mg/kg of body weight parenterally during preweaning (pigs age 77 days) | 1 |
Ceftiofur use | Swine | Grower-finisher | Farm | 5 mg/kg of body weight parenterally during preweaning. Pigs age 155 days | 1 |
Ceftiofur + Amoxicillin Use | Swine | Grower-finisher | Farm | 5 mg/kg ceftiofur of body weight parenterally during preweaning + 10 mg/kg of body weight/day amoxicillin in feed for 14 days. Pigs sampled at age 155 | 1 |
Ceftiofur + Amoxicillin Use | Swine | Weaners | Farm | 5 mg/kg ceftiofur of body weight parenterally during preweaning + 10 mg/kg of body weight/day amoxicillin in feed for 14 days. Pigs sampled at age 84 | 1 |
Amoxicillin use | Swine | Grower-finisher | Farm | 10 mg/kg of body weight/day in feed for 14 days days (pigs age 155 days) | 1 |