Baron, Sandrine and Jouy, Eric and Touzain, Fabrice and Bougeard, Stphanie and Larvor, Emeline and de Boisseson, Claire and Amelot, Michel and Keita, Alassane and Kempf, Isabelle (France)
Veterinary Microbiology (2016)
Fiftymaleandfemalespecific-pathogen-free(SPF)one-day-oldLeghornchickswereobtained. Theywererandomlyassignedtofiveexperimentgroups.Thefirstisolator(A)contained20ceftiofur-treatedbirds,ofwhichtenwereinoculatedwithE.coli369(inoculatedtreatedgroup(IT))andtenkeptasnon-inoculatedcontactbirds(contacttreatedgroup(CT)). Thesecondisolator(B)contained20birdsnottreatedwithceftiofur.Inthisgroup,tenbirdswereinoculatedwiththeE.coli369strain(inoculatednon-treatedgroup(INT))andtenkeptasnon-inoculatedcontactbirds(contact,non-treatedgroup(CNT)).Thethirdisolator(C)housedtenchicksneithertreatedwithceftiofurnorinoculatedwithE.coli369(control). Onthefirstdayoflife(Day0),all20birdsinisolatorAreceivedasubcutaneousinjectionofceftiofur(0.1mgperbird,CEVAXEL50mg/l,CEVA,Libourne,France)whereasthe20chicksinisolatorBwereinjectedwithasterilebuffer.
individualfecalsampleswerecollecteddailyforthe first five days and then on days 14, 26 and 34, the end of the experiment.
AST Method: Multiple Methods
Reference explicitly reports AST breakpoints: False
Reference reports using a MIC table: False
Is Excluded: False
| Country | Sub-Region | Sub-Region Detail |
|---|---|---|
| France | None | None |
| ID | Note | Resolution |
|---|
| Title | Host | Host | Production Stage | Description | ROs |
|---|---|---|---|---|---|
| Ceftiofur use | Chicken | Chicks | Farm | In contact with birds inoculated with E. coli 369; day 34 data | 1 |
| Ceftiofur use | Chicken | Chicks | Farm | Inoculated with E. coli 369; day 34 data | 1 |