Reference | Shelton2009 (10113)

Effects of copper sulfate, zinc oxide, and neoterramycin on weanling pig growth and antibiotic resistance rate for fecal escherichia coli.


Shelton, N. W.; Jacob, M. E.; Tokach, Michael D.; DeRouchey, Joel M.; Amachawadi, R. G.; Shi, X.; Nagaraja, Tiruvoor G.; Nelssen, Jim L.; Goodband, Robert D.; Dritz, Steven S. (United States of America)

Other (2009)

Reference


A total of 180 weanling pigs (PIC TR4 A-1050, initially 11.1 lb and 21 d of age) were used in a 42-d growth trial. Pigs were allotted to pens by initial BW, and pens were assigned to treatments in a random-ized complete block design with both weight and location in the nursery serving as blocking factors. There were 6 pens per treatment with 5 pigs per pen. Treatments were arranged as a 2 A- 2 factorial design with main effects of added copper from CuSO4 (0 or 125 ppm) and added zinc from ZnO (0 or 3,000 ppm from d 0 to 14 and 0 or 2,000 ppm from d 14 to 42) along with an additional treatment with an in-feed antibiotic that providing neomycin (50 g/ton) and oxytetracycline (50 g/ton). The trace mineral premix supplied a base level of 165 ppm zinc and 16.5 ppm copper in all diets. The diets were fed in 2 phases: Phase 1 from d 0 to 14 and Phase 2 from d 14 to 42. Treatment diets were prepared by replacing cornstarch with ZnO, CuSO4, or in-feed antibiotic.

On d 14 and 42, fecal samples were collected from 3 randomly selected pigs per pen.

AST Method: None

Reference explicitly reports AST breakpoints: True

Reference reports using a MIC table: False

Is Excluded: False

Country Sub-Region Sub-Region Detail
United States of America Kansas (State) Manhattan
ID Note Resolution

Factors


Title Host Host Production Stage Description ROs
Copper and zinc use Swine Weaners None Phase 2 diet (day 14 - 42): basal diet with 125 ppm of added Cu from CuSO4 and 2,000 ppm from d14-28 added Zn from ZnO) instead of cornstarch. 1
Copper and zinc use Swine Weaners Farm Phase 2 diet (day 14 - 42): basal diet with 125 ppm of added Cu from CuSO4 and 2,000 ppm from d14-28 added Zn from ZnO) instead of cornstarch. 3
Copper use Swine Weaners Farm Phase 2 diet (day 14-42): basal diet with copper from CuSO4 (125 ppm) instead of cornstarch. 4
Neomycin and oxytetracycline use Swine Weaners Farm Phase 2 diet (day 14-42): basal diet with in-feed antibiotic that providing neomycin (50 g/ton) and oxytetracycline (50 g/ton) instead of cornstarch. 4
Zinc use Swine Weaners Farm Phase 2 diet (day 14-42): basal diet with 2,000ppm added Zn from ZnO from d14-28 instead of cornstarch. 4