Mazurek, Justyna; Bok, Ewa; Stosik, Michał; Baldy-Chudzik, Katarzyna (Poland)
International Journal of Environmental Research and Public Health (2015)
Five groups of pigs underwent same metaphylaxis program; the groups consisted of individuals of different age. Fecal samples were taken from 6-week-old piglets, after the first week of treatment (Piglets 1; P1), from a 7-week-old cohort taking antimicrobials for 2 weeks (Piglets 2; P2), and an 8-week-old cohort taking antimicrobials for 3 weeks (Piglets 3; P3). The sampling also covered two herds of sows that were subjected to the same metaphylaxis program in the past. They were 10 (Sows 1; S1) and 18 weeks (Sows 2; S2) after the end of treatment and did not take any other antimicrobials before the time of sampling. The medical program was applied after the diagnosis of colibacillosis. The antimicrobials were administered in the form of medicated fodder which contained trimethoprim/sulfamethoxazole, 15–30 mg of active substance per 1 kg of body weight per day.
Fecal samples.
AST Method: None
Reference explicitly reports AST breakpoints: True
Reference reports using a MIC table: False
Is Excluded: False
| Country | Sub-Region | Sub-Region Detail |
|---|---|---|
| Poland | Lubuskie (Voivodship) | None |
| ID | Note | Resolution |
|---|
| Title | Host | Host | Production Stage | Description | ROs |
|---|---|---|---|---|---|
| Duration of trimethoprim-sulfamethoxazole use | Swine | Weaners | Farm | P2 (7-wk-old cohort, sampled after 2 wks of AMU) P1 (6-wk-old cohort, sampled after 1 wk of AMU). Metaphylactic treatment with trimethoprim-sulfamethoxazole as medicated fodder, 15–30 mg active substance/1 kg body weight/day, to post-weaning piglets. | 2 |
| Duration of trimethoprim-sulfamethoxazole use | Swine | Weaners | Farm | P2 (7-wk-old cohort, sampled after 2 wks of AMU) P1 (6-wk-old cohort, sampled after 1 wk of AMU). Metaphylactic treatment: trimethoprim-sulfamethoxazole as medicated fodder, 15–30 mg active substance/1 kg bw/day, to post-weaning piglets. | 7 |
| Duration of trimethoprim-sulfamethoxazole use | Swine | Weaners | Farm | P3 (8-wk-old cohort, sampled after 3 wks of AMU) P1 (6-wk-old cohort, sampled after 1 wk of AMU). Metaphylactic treatment with trimethoprim-sulfamethoxazole as medicated fodder, 15–30 mg active substance/1 kg body weight/day, to post-weaning piglets. | 2 |
| Duration of trimethoprim-sulfamethoxazole use | Swine | Weaners | Farm | P3 (8-wk-old cohort, sampled after 3 wks of AMU) P1 (6-wk-old cohort, sampled after 1 wk of AMU). Metaphylactic treatment: trimethoprim-sulfamethoxazole as medicated fodder, 15–30 mg active substance/1 kg bw/day, to post-weaning piglets. | 7 |
| Duration of trimethoprim-sulfamethoxazole use | Swine | Sows | Farm | S2 (Sows 18 weeks after end of treatment, these are 6 month old first parity sows) vs S1 (Sows 10 weeks after end of treatment, these are 4.5 month old gilts). These herds were subjected to the same metaphylactic program when they were post-weaning piglet | 2 |