Reference | Lowrance2007 (10043)

Changes in antimicrobial susceptibility in a population of Escherichia coli isolated from feedlot cattle administered ceftiofur crystalline-free acid.


Lowrance, T. Courtney; Loneragan, Guy H.; Kunze, David J.; Platt, Tammy M.; Ives, Samuel E.; Scott, H. Morgan; Norby, Bo; Vet, Cand Med; Echeverry, Alejandro; Brashears, Mindy M. (United States of America)

American Journal of Veterinary Research (2007)

Reference


A cohort study was conducted. Steers were housed in pens (5 pens with 10 steers and 1 pen with 11 steers). Five steers in each pen were administered CCFA, and 5 served as control steers (1 pen had 6 control steers). The CCFA administration included a single-dose regimen (6.6 mg/kg, SC, on day 0), two-thirds–dose regimen (4.4 mg/kg, SC, on day 0), and 3-dose regimen (6.6 mg/kg, SC, on days 0, 6, and 13)

Fecal samples were collected on days 0, 2, 6, 9, 13, 16, 20, and 28. Fecal samples were collected immediately before CCFA administration

AST Method: Broth Microdilution

Reference explicitly reports AST breakpoints: False

Reference reports using a MIC table: True

Is Excluded: False

Country Sub-Region Sub-Region Detail
United States of America None None
ID Note Resolution

Factors


Title Host Host Production Stage Description ROs
administered CCFA Cattle None Farm administered CCFA as a single-dose regimen (6.6 mg/kg, SC, on day 0) 3
CCFA 1 Dose Regimen Cattle Finishers Farm Ceftiofur crystalline-free acid (CCFA) administered as a single dose (6.6 mg/kg, SC). 15
CCFA 2/3 Dose Regimen Cattle Finishers Farm Ceftiofur crystalline-free acid (CCFA) administered as a two-thirds dose regimen (4.4 mg/kg, SC). 15
CCFA 3 Dose Regimen Cattle Finishers Farm Ceftiofur crystalline-free acid (CCFA) administered as a 3-dose regimen (6.6 mg/kg, SC, Day 0, 6, 13). 15