Reference | Juntunen2011 (10012)

A Finnish farrowing farm with 950 sows was selected for this study based on on-going danofloxacin and consecutive tylosin usage prescribed by a local veterinarian. Piglets were weaned at age of 3-4 weeks. Pigs with clinical symptoms of postweaning diarrhoea were treated with intramuscular danofloxacin (25mg/mL injection) for three days (1 mL daily - approx 3.3 mg/kg). Danofloxacin treatment was based on susceptibility testing of the causative agent, E.coli All pigs were routinely administered tylosin twice daily in feed (100mg/kg, equivalent to body wt dose of 3-6mg/kg/day) A 10-day period of tylosin-supplemented was administered 11 days after weaning because of a persistent diarrhoea problem at the weaning unit. 12 pigs received danofloxacin after 5 days at the weaning unit (group A) and 15 pigs remained as controls (group B). The pigs were reared in 3 pens each containing animals from both groups. The MIC determination of the C.coli isolates was performed with the agar dilution method.

Faecal samples were collected from 27 ear-tagged pigs at 6 time points between Oct and Dec 2009. Individual faecal samples were taken from the rectum with Probact transport swabs ( Juntunen et al., 2010).

AST Method: Agar Dilution

Reference explicitly reports AST breakpoints: True

Reference reports using a MIC table: True